Ibuprofen (Motrin®, Advil)

Ibuprofen (Motrin®, Advil) is a non-steroid, non-narcotic analgesic, anti-inflammatory and antipyretic drug (NSAID). Ibuprofen is used to reduce fever, relieve mild to moderate pain and inflammation caused by toothache, back pain, arthritis, menstrual cramp.

Active ingredient is Ibuprofen.

Inactive ingredients are propylene glycol, titanium dioxide, carnauba wax, colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose, magnesium stearate, microcrystalline cellulose.

Dispense:

Ibuprofen should be taken with food or milk to lessen the stomach irritation.  Maximum amount for an adult is 800 mg per dose every 4-6 hours, not to exceed 3200 mg per day

Ibuprofen chewable tablet (50 mg) must be chewed before swallowing.

Side effects:
  1. Heartburn
  2. Nausea and vomiting 
  3. Diarrhea
  4. Constipation
  5. Indigestion
  6. Bloating and flatulence
  7. Gastric or duodenal ulcer with bleeding or perforation
  8. Dizziness, headache, nervousness
  9. Numbness, tingling, burning sensation (Paresthesia)
  10. Hallucinations
  11. Insomnia, depression, confusion
  12. Meningitis
  13. Ringing in the ears (Tinnitus)
  14. Anemia
  15. Loss appetite
  16. Edema, fluid retention
  17. Palpitation
  18. Elevated blood pressure
  19. Acute renal failure
  20. Dry eyes and mouth, gingival ulcer
Contraindications:
  • Patient should not take Ibuprofen after coronary artery bypass graft surgery
  • Do not use NSAIDS with patients who have cardiovascular disease due to the increasing risk of myocardial infarction and stroke.
Drug interactions:
  • Patient should not take Aspirin with Ibuprofen due to the potential adverse reaction increased 
  • Ibuprofen can reduce the effectiveness of Furosemide and Thiazides in some patients
  • Lithium taken with Ibuprofen may reduce renal Lithium clearance causing Lithium toxicity
  • Methotrexate taken with Ibuprofen may enhance the toxicity of Methotrexate
  • Warfarin-type anticoagulants taken with Ibuprofen may increase GI bleeding
Note:  
Carefully consider the potential risks and benefits of this pharmaceutical to other alternative options before using it.

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